[Larsen syndrome: multicenter study of 12 new cases. Diagnosis, planning and results of treatment]

Published online: Sep 27 1994

A Rodríguez, B Asenjo, R Dominguez, and R Lemaire.

Service de Chirurgie de l'Appareil Locomoteur (Orthopédie-Traumatologie), Centre Hospitalier Universitaire du Sart-Tilman, Liège, Belgique.


Larsen's syndrome is characterized by the association of congenital knee, hip and elbow dislocations, characteristic facial abnormalities, joint hyperlaxity, and other inconstant malformations. A review is made after description of 12 new cases from a multicenter study. A partial modification of diagnostic criteria is proposed, based on the analysis of the frequency and localization of the deformities. Radiological aspects, surgical indications, clinical evolution, complications and late results are presented, with emphasis on lower extremity problems. Good clinical results are more remarkable in the children treated early. Periodic follow-up is obligatory for good therapeutic results.