Idiopathic multicentric osteolysis : A case report and literature review.
Published online: Jun 27 2005
Rishi SINGHAL, Javed SALIM, Paul WALKER
From the North Lincolnshire and Goole Hospitals NHS Trust, Scunthorpe, United Kingdom
Abstract
Osteolysis is defined as destruction of bone by
resorption. Usually this resorption is associated
with some underlying disorder and classified as
secondary osteolytic syndromes.
Primary idiopathic osteolysis is rare. It is characterised
by the spontaneous onset of bone resorption
without known causative factors. Bones which
previously appeared normal begin to undergo partial
or complete resorption. This process continues
for years, until eventually it ceases spontaneously.
The exact pathogenetic mechanism of this osteolysis
remains unknown.
We present a unique case of idiopathic osteolysis,
that does not fit into the previously described
patterns of the disease.