External application of hypertonic salt solution
for treatment of posttraumatic oedema
Published online: Aug 27 2005
Hakan ATALAR, Osman Y. YAVUZ, Ismail URAS, Hakan SELEK, Aziz ERAKAR, Ugur SAYLI
From Department of Orthopaedic Surgery, Ankara, Turkey
Abstract
In 20 New Zealand rabbits (two groups of 10 rabbits
each), hind limb circumference and anterior compartment
pressure were measured following ketamin
anaesthesia (time zero). During the same anaesthesia,
closed transverse proximal tibial shaft fractures were
created in both groups. Twenty-four hours after the
fractures, during a second anaesthesia, limb circumference
and compartment pressure were measured as
before, and fractured limbs were fixed to the rabbits'
bodies. At the same time, treatment was started : one
group received external application of saturated salt
solution and the other group received intermittent
ice application.
During 48 hours of treatment (from 24 to 72 hours)
in the saturated salt solution group, the mean limb
circumference decreased from 125.70 ± 9.93 mm to
115.70 ± 8.78 mm (p = 0.005) and the mean compartment
pressure decreased from 18.30 ± 1.70 mmHg to
12.40 ± 1.77 mmHg (p = 0.005). In the control group,
the mean limb circumference decreased from
127.85 ± 7.47 mm to 122.00 ± 6.83 mm (not significant)
and the mean compartment pressure decreased
from 19.57 ± 1.27 mmHg to 17.85 ± 2.67 mmHg (not
significant). In short, differences in compartment
pressure and limb circumference before and after
treatment were statistically significant in the saturated
salt solution group (p = 0.005) but not in the
control group.