C-reactive protein kinetics and its predictive value in orthopedic (trauma) surgery: A systematic review

Keywords:

C-reactive protein ; diagnostic tool ; orthopedic surgery ; surgical site infection


Published online: Dec 30 2018

J. Kruidenier , S.A. Dingemans , S. van Dieren , V.M. de Jong , J.C. Goslings , T. Schepers

From the Trauma Unit, Amsterdam UMC, Amsterdam, The Netherlands

Abstract

In Orthopedic Trauma Surgery (OTS), C-reactive- protein (CRP) is a widely used marker for the diagnosis of postoperative wound infections (POWI’s) and other complications. The aim of this systematic review was to describe specific CRP kinetics and to evaluate the diagnostic value of CRP for te detection of post-operative complications in OTS. The same pattern is reported consistently, where the highest levels of CRP are found at post-operative-day two or three, returning to normal in three weeks. Amplitude varies per procedure. Persistently high CRP levels or secondary increases may indicate complications. A low CRP may be used to rule out complications.

About this issue

Volume 84, issue 4.

Dec 2018.

 

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